La Larria Botanicals

        Herbal Formulary 


Member:  American Botanical                             Council

                                                              Research on Multiple Sclerosis

MS is a grizzly disease with both physical and psychological disabilities.  Progress in effective medicine is gut-wretchedly slow.  Alternatives to western medicine are palliative at best.  This page is devoted to recent research which might shed light on alternatives to the immuno-suppressive medications now available. For MS Research click the button at left.


     From the NIH Site:     ​​Eight Clinical Trials for Chaparral

1.  Pharmacokinetic and Efficacy Study of Nordihydroguaiaretic Acid (NDGA) in Non Metastatic Recurrent Prostate Cancer
​2.  Nordihydroguaiaretic Acid in Treating Patients With Nonmetastatic Relapsed Prostate Cancer
3.  Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma
4.  Study of Intralesional Injection of M4N in Patients With Refractory Malignant Tumors of the Head and Neck
5.  Phase 1 Study of Terameprocol (EM-1421, (Tetra-O-Methyl Nordihydroguaiaretic Acid ) in Patients With Leukemia
6.  A Phase 1 Continuous Intravenous Infusion Study of Terameprocol (EM-1421 (Tetra-O-Methyl Nordihydroguaiaretic Acid ) in Subjects With Refractory Solid Tumors
7.  A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia
8.  Dose Escalation Study of EM-1421, (Tetra-O-Methyl Nordihydroguaiaretic Acid ) for the Treatment of Recurrent or Refractory Solid Tumors I'm checking to see if these Links are still valid.


Research Paper:   De Novo Sequencing of Hypericum perforatum Transcriptome to Identify Potential Genes Involved in the Biosynthesis of Active Metabolites: "Hypericum perforatum L. (common St. John’s wort) is a widely known medicinal herb used mostly as a remedy for depression [1]. It also has other broad pharmacological activities, such as anti-tumor, anti-inflammatory, antiviral, antioxidant, anti-cancer, and antibacterial properties [2], [3]. Human health is benefited because of this diversity of active ingredients within various chemical groups. Its major active metabolites – hypericins, hyperforins, and melatonin – belong to the naphthodianthrones, phloroglucinols, and alkaloids, respectively. Xanthones and flavonoids have also been identified in extracts from this plant [4].”  Click on St. John’s wort Research at left for more.

Featuring Botanicals, Tinctures, Soaps, Shampoos, Lip Balms and Creams

                                                         Made From:

      Salvia miltorhiza Organic Root                        Fresh wildcrafted St. John's wort (Hypericum  perforatum)

   Salvia columbaria Wildcrafted Root       Fresh wildcrafted Chaparral (Larrea tridentata, Greasewood or Creosote bush)

        Gotu kola Organic Root                             Fresh wildcrafted Jojoba leaf extract (Simmondsia chinesis)

     Valeriana wallichii Organic Root                         Fresh wildcrafted Chinchweed (Pectis papposa)

      Ginkgo biloba Organic Leaf                             Fresh Ashwagandha Organic Root  (Withania somnifera)

    Hawthorn Organic Berries & Tops                                      Black cohosh Organic Root

                                                                              Goldenseal Organic Root (Hydrastis cacadensis)

                                                                                         Echinacea purpurea Organic Root

                                                                               Azulene (Essential oil from German Chamomile)


                                            Data on ST. JOHN'S WORT updated May 2014

Traditional Usage:  St. John's wort oil and tinctures have been used for relieving pain to help those with fibromyalgia, neuralgia, sciatica and other muscle and nerve pain.  St. John's wort is restorative and nourishing to the nervous system helping with irritability, depression, helps calm anxiety, is supportive for Seasonal Affective Disorder, to help rebuild damaged nerves, for muscle and joint aches and pain, to relax restless leg syndrome.  


                                                                 









































Research Title:  Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivatives:  "Creosote bush, Larrea Tridentata, is known as chaparral or greasewood in the United States and as gobernadora or hediondilla in Mexico.  Nordihydroguaiaretic acid (NDGA), the main metabolite of the creosote bush, has been shown to have promising applications in the treatment of multiple diseases, including cardiovascular diseases, neurological disorders and cancers.  Creosote bush is a promising agent of North American herbal medicine, and it has extensive pharmacological effects and specific mechanisms of action.  This review provides an update of recent in vitro and in vivo research about NDGA and describes experimental studies using NDGA as antioxidant.  Also, potential medical uses based on the effects of NGDA on cardiovascular, immune and neurological systems, cancer, tissue engineering...".  More to come on specific actions, if you want the whole article, please email me and I will send it to you.

                                         The anti bacterial activity of Larrea tridentata  (Chaparral)

Research Title:  The bioactivity of plant extracts against representative bacterial pathogens of the lower respiratory tract: “The CLO and MET extracts of L. tridentata showed different activity spectra. Verastegui et al. reported that ethanolic extract of L. tridentata was active against L. monocytogenes, Clostridium perfringens, Shigella dysenteriae, Yersinia enterocolitica and Proteus vulgaris, with a MIC ranging from 10 to 19 μg/ml, yet they did not find activity against E. coli [21]. We found that CLO and MET extracts of L. tridentata showed activity against L. monocytogenes and no activity against E. coli. This confirms the antibiotic activity of L. tridentata extracts; however, it is difficult to compare our results directly with Verastegui et al. because we did not include these ethanolic extracts in our study.”  If you want the whole article, please email me and I will send it to you.


And the disclaimer:  this information is not intended to diagnose, treat, cure, or prevent any disease, please consult your health care professional.


                   

HAND MADE IN SMALL BATCHES

 

Our botanicals are made in small batches to insure tight quality control. 

FRESH HARVESTED

 

The greasewood and St. John's Wort are wildcrafted, freshly harvested tops and flowers.   Extracts made from fresh herbs are more efficacious.

QUALITY

                          

Only the finest herbs are sourced and used in our formulations..

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                                                ​Research on Ashwagandha

Ashwagandhaenhances the function of the brain and nervous system and improves the memory. It improves the function of the reproductive system promoting a healthy sexual and reproductive balance. Being a powerful adaptogen, it enhances the body's resilience to stress. Ashwagandha improves the body's defense against disease by improving the cell-mediated immunity. It also possesses potent antioxidant properties that help protect against cellular damage caused by free radicals. For more information on Ashwagandha please click on the button at left.

 Data on Chaparral, Larria tridentata

From:  Ross, R.Ph. Pelton, Lee Overholser.  Chaparral    “In the deserts of the southwest United States, when the damp breeze that announces an approaching thunderstorm blows across the valleys, it carries the pungent aroma of the common desert shrub chaparral, or the creosote bush.

Background Chaparral (scientifically called Larrea tridentata or Larrea diver-icata} grows from four to eight feet tall, and has small, dark green leaves and brittle stems. It covers hundreds of square miles in the desert plains and slopes of southern California and Arizona, up to an elevation of five thousand feet. (8) The Cahuilla Indians of the Palm Springs, California, area make a general-health tonic tea from its leaves, which they sweeten with honey. (2)The medicinal tea is used for many different diseases, from colds to intestinal complaints and cancer. (6) In 1942 scientists at the University of Minnesota isolated nordihydroguaiaretic acid (NDGA) as the most significant chemical component of chaparral. (12) NDGA was used to preserve butter in the tropics during World War II, and is used to preserve other fats and oils, because it is a very powerful antioxidant. Dr. Mora, from the University of Auburn in Auburn, Alabama, has found that NDGA attacks bacteria, yeast, viruses, fungi, and cancer cells...."
Full article click: Chaparral Herbal Research at left.